Tag Archives: Intrinsic factor

The Most Overlooked Risk of Stomach Bloating

Gassy, painful stomach bloating from indigestion may mean that you need more of an essential vitamin in your blood supply. If your gut feels like a war zone, then experts recommend getting tested for vitamin B12 deficiency, a form of anemia linked to gastritis.

The Most Overlooked Risk of Stomach Bloating

Stomach bloating? Check your B12.

B12 deficiency in the gut

To digest vitamin B12 from food, you need to have a healthy ecosystem in your gastrointestinal tract. Good bacteria winning the battle over the bad, proper absorption of nutrients, and all that.

But for many, damage to the parietal cells of the stomach, acid reflux, and medication overuse lead to a vicious cycle of vitamin B12 anemia that feeds into constant symptoms of fatigue, stomach bloating, sore muscles, dizziness, and memory problems.

Symptoms of pernicious anemia include stomach bloating, and also diarrhea, heartburn, brain fog, painful numbness in the hands and legs, cognitive impairments, and more.

Stomach bloating and other symptoms

The following symptoms, if they occur often, may indicate a breakdown in your digestive system that requires immediate treatment in order to prevent vitamin B12 deficiency anemia:

  • Acid reflux
  • Heartburn
  • Vomiting
  • Abdominal pain
  • Chest pains
  • Shortness of breath
  • Nausea
  • Stomach bloating
  • Hardening of the stomach
  • Loss of appetite
  • Difficulty swallowing
  • “Lump” in your throat
  • Diarrhea
  • Constipation
  • Frequent burping
  • Flatulence

Vitamin B12 malabsorption

Foods that contain vitamin B12 are meats, chicken, fish, milk, and eggs. Generally, as long as you eat a steady non-vegan diet, you’re guaranteed a plentiful supply of vitamin B12 for good health…

…Unless you suffer from vitamin B12 malabsorption. The inability to break down vitamin B12 happens when you don’t have enough intrinsic factor, a digestive enzyme produced in your stomach that helps to grab vitamin B12 from food and “escort” it through your intestines and into your blood supply.

Gastritis (stomach inflammation) is one of the most common causes of vitamin B12 malabsorption.

Yes- stomach damage can cause vitamin B12 deficiency.

What Causes Vitamin B12 Malabsorption?

Gastrointestinal disorders

If you suffer from inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, then your risk of becoming ill from pernicious anemia– severe vitamin B12 deficiency- is greater than most.

Damage to the walls of the stomach and intestinal tract, particularly the bottommost part (ileum), makes it impossible to get crucial vitamin B12 into your blood stream without direct insertion of nondietary liquid vitamin B12 supplements.

Other illnesses that cause enough gastrointestinal distress to interfere with vitamin B12 absorption include fibromyalgia, migraines, celiac, lupus, and chronic stomach ulcers.                       

Gastro surgery

If you’re an IBD patient who has elected for corrective surgery to treat chronic stomach bloating, indigestion, ulcers, and stomach pain, then you must supplement with high doses of vitamin B12 from a reliable source, in order to prevent becoming anemic.

Weight loss surgery recipients who undergo gastric bypass are also included in that risk category for pernicious anemia.

Autoimmune disorders

You may not able to get enough vitamin B12 simply because your body identifies intrinsic factor as a danger, and attacks it. If you suffer from immune system dysfunctions such as rheumatoid arthritis, lupus, or celiac disease, then it’s important to get your vitamin B12 levels checked regularly.

Better yet, begin a routine of supplemental vitamin B12 as a preventive measure against pernicious anemia. There’s no danger of taking too much vitamin B12, since it is safe in all amounts.

Please tell us…

Have you been experiencing stomach bloating and other signs of digestive disorders, but didn’t realize they were connected to vitamin B12 deficiency?

If you suffer from gastrointestinal issues such as Crohn’s disease, gastroesophageal disorder (GERD),  or ulcerative colitis, do you feel that you ‘re getting enough vitamin B12 from your doctor to combat deficiency?

Image by Ohmega1982

 

 

Vitamin B12 Deficiency and Osteoporosis

Just in the news- scientists have discovered a connection between vitamin B12 deficiency and osteoporosis that may change the way doctors treat bone loss. To promote good bone health, the key may be in sustaining maximum levels of vitamin B12 in your blood supply.

Vitamin B12 Deficiency and Osteoporosis

Vitamin B12 deficiency and osteoporosis

Vitamin B12 deficiency is a form of anemia that occurs when your vitamin B12 levels in the blood drop to a dangerous low. In most people, B12 deficiency occurs from vitamin B12 malabsorption- the inability to digest vitamin B12 from foods such as meat, chicken, and fish.

For many people, this occurs as an autoimmune impairment, an improper response to intrinsic factor, a protein needed to completely break down and utilize vitamin B12.

Among the many ailments attributed to vitamin B12 deficiency caused by lack of intrinsic factor, increased risk for osteoporosis was the focus on a study led by researchers from the Wellcome Trust Sanger Institute.

“We were amazed to find a new system that controls bone mass through a protein expressed, of all the places, in the stomach.” – Dr Pablo Roman-Garcia, study author

Vitamin B12, the liver, and bone health

In the study, scientists found dramatic bone loss in mice born to mothers with vitamin B12, noting that low vitamin B12 levels accounted for nearly 70% less bone mass than healthy specimens.

While injecting vitamin B12 didn’t improve bone health, researchers did find that vitamin B12 supplements had a therapeutic effect on liver cells.  On closer inspection, they noticed that subjects with vitamin B12 deficiency were unable to produce taurine, a natural substance produced in the liver that promotes good bone cell production in preventing osteoporosis.

“While the importance of taurine is yet to be fully understood, this research shows that vitamin B12 plays a role in regulating taurine production and that taurine plays an important role in bone formation.” -Dr Vidya Velagapudi, Institute for Molecular Medicine Finland.

Previous studies also confirm these findings, such as one that examined children in Turkey born to mothers with vitamin B12 deficiency where taurine deficiency was also present.

Also, scientists from the Institute for Molecular Medicine Finland saw positive results in bone cell production and taurine synthesis when vitamin B12 supplements were provided.

Helpful Links

More details on the study about vitamin B12 deficiency and osteoporosis can be found here: Pathway between gut and liver regulates bone mass

Watch the video on YouTube: Vitamin B12: A Bone Pathway

Vitamin B12- Essential for Chronic Pain Management

Image by renjith krishnan