Category Archives: medication

Could Antioxidant Treatment Reduce Arthritis Pain?

pain, rheumatoid arthritis, arthritisAre you looking for a more natural way to deal with your rheumatoid arthritis pain? Some prescription medicines  may make you feel foggy, cause stomach ulcers, or  cause weight gain.  However, recent studies have shown that more natural antioxidants may help reduce rheumatoid arthritis pain without so many side effects.

What is Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is an autoimmune disorder affecting the joints and other body tissues. In autoimmune diseases, the immune system wrongly attacks the body. Therefore, damage can be caused in the skin, eyes, lung, heart, and blood vessels.  Also, damage to the joint lining causes deformity in the joints, such as in the hands. Because of this damage, daily tasks and simple movement can become more difficult and painful.

RA tends to affect smaller joints first such as those in the fingers and toes. Some symptoms of the condition include:

  • Tender, swollen joints
  • Joint stiffness
  • Fatigue
  • Fever
  • Weight loss

Larger joints such as those in hips and knees may be affected as the disease progresses. However, nearly 40-percent of those affected by the condition have non-joint symptoms. The eyes, salivary glands, blood vessels, and nerve tissues are just some of the other body tissues that can be affected by RA.

Current RA Treatments

The most common treatment to arthritis pain are NSAIDS, or non-steroidal anti-inflammatory drugs. These drugs reduce pain and inflammation. Lower strength forms of NSAIDs can be purchased over-the-counter. However, long-term use of such medicines can cause symptoms such as:

  • ringing in your ears
  • stomach pain and ulcers
  • heartburn
  • heart problems
  • liver and kidney damage

Other treatments for RA include steroids and disease-modifying antirheumatic drugs (DMARDS). Long term use of steroid though can thin bones and cause weight gain.  DMARDS such as methotrexate can slow progress of the disease. A newer class of DMARDs called biologic agents, which include Humira and Xeljanz, work to reduce inflammation. However, these medicines may have side effects such as liver damage and increased risk of infections.

Antioxidants and RA Pain

Mediterranean diet, olive oil, health fats, olives, tomatoes, vegetables, heart healthA journal article in the Frontiers in Nutrition suggested that fiber-rich and antioxidant-rich foods may decrease inflammation in those with RA. Furthermore, it was suggested to get such benefits from some of the following foods and drinks.

  • dried plums
  • pomegranates
  • whole grains
  • turmeric
  • olive oil
  • green tea
  • blueberries

Other recent research has confirmed that antioxidant treatment may be helpful to those with RA. For example, a 2003 study talked about how the antioxidant defense system is weakened in RA patients. Therefore, researchers suggested therapy including standard drugs along with antioxidants to help reduce tissue damage in such patients.

In addition to these studies, more recent research has also shown potential for antioxidant treatment of RA. For example, a 2008 study found that antioxidant therapy combined with lower doses of standard drugs may help reduce tissue damage. Due to these lower doses of prescribed drugs, such treatments may help reduce harmful side effects.

Other Ways to Reduce Inflammation

  • Stop smoking since this activity can constrict blood vessels and cause inflammation in the body and its tissues.
  • Limit alcohol consumption: If you do decide to have an alcoholic drink, choose phytonutrient-rich red wine that contains polyphenols such as resveratrol. Also, be sure to limit consumption to no more than 1 standard drink a day for women or 2 standard drinks a day for men. For example, a standard drink of wine is equal to 5 ounces.
  •  Take probiotics through fermented food such as yogurt or through a supplement such as Biovia 30 by Vita SciencesBiovia 30 contains 30 million strains of diverse good bacteria that helps to strengthen your immune system. Probiotics can help restore good bacteria in your gut.  When your body has more good bacteria, it makes it easier to fight off bad bacteria that may be damaging your immune system.  Therefore, a stronger immune system can help fight off inflammation in the body.

Furthermore, recent research shows a link between deficits in the intestinal microbiome and autoimmune disease. Although more studies need to be done, it is suggested that treatment of gut microbiota may be the key to improving effective treatments for such conditions as RA.

-written by Staci Gulbin, MS, MEd, RD, LDN

Sources:

Horta-Baas, G., Romero-Figueroa, M. del S., Montiel-Jarquín, A. J., Pizano-Zárate, M. L., García-Mena, J., & Ramírez-Durán, N. (2017). Intestinal Dysbiosis and Rheumatoid Arthritis: A Link between Gut Microbiota and the Pathogenesis of Rheumatoid Arthritis. Journal of Immunology Research2017, 4835189. http://doi.org/10.1155/2017/4835189

Jaswal, S., et al. (December 2003) “Antioxidant Status in Rheumatoid Arthritis and role of Antioxidant Therapy.” Clinica Chimica Acta, 338(1-2): 123-129.

Mayo Clinic (August 9, 2017) “Rheumatoid Arthritis.” 

Medline Plus (November 8, 2017) “These Foods May Help Ease Rheumatoid Arthritis Pain.” 

Van Vugt, R. M., Rijken, P. J., Rietveld, A. G., van Vugt, A. C., & Dijkmans, B. A. C. (2008). Antioxidant intervention in rheumatoid arthritis: results of an open pilot study. Clinical Rheumatology27(6), 771–775. http://doi.org/10.1007/s10067-008-0848-6

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Could Probiotics Improve Health Outcomes After Injury?

probiotic, fermented food, yogurt, sauerkraut, apple cider vinegar, gut health, digestion

Fermented foods can provide natural sources of good bacteria.

From hearing your stomach grumble when it’s hungry to the gurgling sounds of indigestion, the gut reminds us everyday of its important presence in our health. Gut bacteria are vital to keeping balance in the body. Also, gut bacteria make sure that any food consumed is being used for energy.  However, recent research has shown that gut bacteria may also be crucial for positive health outcomes after injury.

What is gut bacteria?

Gut bacteria is part of a community of microorganisms such as fungi and viruses that live in the gut microbiome. Also, gut bacteria get along well with the cells of the gastrointestinal (GI) tract and are not known for causing disease. Functions of gut bacteria include:

  • breaking down nutrients to be used for energy
  • protecting the body from toxic invaders
  • breaking down and eliminating drugs from the body

Imbalances of gut bacteria in the body can lead to conditions such as inflammatory bowel disease (IBD).  Also, gut bacteria live in harmony with the immune system and work together to keep the body safe from “bad” bacteria. However, an imbalance in “good” versus “bad” bacteria in the gut could have an impact on immune system function.

Gut bacteria and Injury

A study of 12 critically injured adults in the journal Trauma Surgery & Acute Care Open looked at the status of gut bacteria health over time. Stool samples were taken 24 hours and 72 hours after admission to the hospital.  After 72 hours, three types of bacteria had been depleted in the injured group, while two types of bacteria had risen.  More studies need to be done to explore this finding more. However, the researchers suggest that gut bacteria structure could affect patient outcomes after traumatic injury.  Furthermore, probiotics may be one future treatment to help improve patient outcomes in these cases.

What are probiotics?

Probiotics, which means “for life,” are live microorganisms meant to have positive health benefits.  You may see on store shelves many probiotic medicines containing bacteria from the groups Lactobacillus and Bifidobacterium.  However, since each strain of bacteria benefits a different function in the gut, the more types of strains in a probiotic, the potentially greater health impact. Probiotics may be helpful in preventing diarrhea caused by infections and antibiotics as well as in treatment of those with irritable bowel syndrome (IBS). Basic functions of probiotics may include:

  • maintaining a diverse community of microorganisms
  • maintain a protective barrier for the gut to keep out pathogens
  • recover balance after infection, antibiotic treatment, or other disturbances
  • Stop growth of and fight off unwanted microorganisms
  • Nourish and strengthen the immune system

Biovia30 by VitaSciences provides 30 million colony forming units per dose of diverse strains to help restore balance in the gut and promote immune system strength. Furthermore,  Biovia30 contains various strains of Bacillus, Lactobacillus, and Bifidobacterium to help you build up “good” bacteria stores and keep “bad” bacteria out.

Other ways to protect the gut

  • Eat plenty of fruits, vegetables, and other fiber-rich foods to help promote diversity of gut bacteria.
  • Stop smoking or don’t start since smoking can negatively affect gut bacteria and the immune system. Not only does smoking constrict blood vessels, but it also causes inflammation in the body which can cause cell damage.
  • Find healthy ways to manage stress such as yoga, meditation, or exercise since stress can alter gut bacteria populations. Stress is one of the contributing factors of IBS.
  • Lower saturated fat intake to help lower numbers of inflammatory microbes in the gut.
  • Consume phytonutrients such as polyphenols and tannins found in colorful berries, beans, nuts, seeds, and teas. These compounds can nourish microbes in the digestive tract.

Probiotics shown great promise for helping to treat various health conditions. However, potential benefits of probiotics must be confirmed by further research. Please contact your healthcare provider before starting any new supplement regimen.

Sources:

Conlon, M. A., & Bird, A. R. (2015). The Impact of Diet and Lifestyle on Gut Microbiota and Human Health. Nutrients, 7(1), 17–44. http://doi.org/10.3390/nu7010017

Jandhyala, S. M., Talukdar, R., Subramanyam, C., Vuyyuru, H., Sasikala, M., & Reddy, D. N. (2015). Role of the normal gut microbiota. World Journal of Gastroenterology : WJG, 21(29), 8787–8803. http://doi.org/10.3748/wjg.v21.i29.8787

Medline Plus (October 26, 2017) “Gut Bacteria May Change Rapidly After Severe Injury.”

National Center for Complementary and Integrative Health (October 2016) “Probiotics: In Depth”

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